GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs7178424 | 1 | rs62008532 | chr15:62365877 | VPS13C | chr15:62144592-62352647:- | -0.1 | -3.66 | 0.000284 | Height |
| THCA | cis | rs3105593 | 1 | rs62017189 | chr15:50922032 | SPPL2A | chr15:50999739-51057910:- | 0.26 | 7.04 | 6.76E-12 | QT interval |
| THCA | cis | rs3105593 | 1 | rs62017206 | chr15:50955626 | SPPL2A | chr15:50999739-51057910:- | 0.29 | 7.44 | 4.83E-13 | QT interval |
| THCA | cis | rs3105593 | 1 | rs62017210 | chr15:50960620 | ATP8B4 | chr15:50150436-50411419:- | -0.11 | -3.43 | 0.000665 | QT interval |
| THCA | cis | rs3105593 | 1 | rs62017210 | chr15:50960620 | SPPL2A | chr15:50999739-51057910:- | 0.28 | 7.36 | 7.95E-13 | QT interval |
| THCA | cis | rs12908161 | 1 | rs62019464 | chr15:85294469 | GOLGA6L5 | chr15:85047738-85060078:- | -0.14 | -3.75 | 0.0002 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62019464 | chr15:85294469 | LOC388152 | chr15:84867600-84898920:- | -0.47 | -7.95 | 1.35E-14 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62019464 | chr15:85294469 | NMB | chr15:85198362-85201802:- | 0.36 | 7.69 | 8.22E-14 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62019469 | chr15:85321220 | GOLGA6L5 | chr15:85047738-85060078:- | -0.15 | -3.81 | 0.000156 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62019469 | chr15:85321220 | LOC388152 | chr15:84867600-84898920:- | -0.48 | -8.08 | 5.36E-15 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62019469 | chr15:85321220 | NMB | chr15:85198362-85201802:- | 0.35 | 7.43 | 5.01E-13 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62021219 | chr15:85256159 | GOLGA6L5 | chr15:85047738-85060078:- | -0.15 | -3.86 | 0.000128 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62021219 | chr15:85256159 | LOC388152 | chr15:84867600-84898920:- | -0.48 | -8.09 | 5.01E-15 | Schizophrenia |
| THCA | cis | rs12908161 | 1 | rs62021219 | chr15:85256159 | NMB | chr15:85198362-85201802:- | 0.37 | 7.72 | 6.74E-14 | Schizophrenia |
| THCA | cis | rs950169 | 1 | rs62026530 | chr15:84775840 | GOLGA6L5 | chr15:85047738-85060078:- | -0.21 | -5.4 | 1.07E-7 | Schizophrenia |